NOTE: Cats also can develop pneumonic plague, and cat to human transmission has been reported. Domestic pets or rodents can carry the infected flea into the house. Plague is a disease caused by Yersinia pestis, a naturally-occurring bacterium found in many areas around the world, including the United States.There are several forms of plague, including pneumonic, bubonic, and septicemic plague. Bubonic plague: via the bite of infected fleas. Diagnosis of infection Most often transmitted by the bite of infected rodent fleas. Pneumonic plague: human-to-human via air-borne droplets associated with coughing. Plague may cause massive, often suppurative lymphadenopathy (buboes), severe pulmonary infection, and/or septicemia. Primary plague pneumonia has a shorter incubation period of 1–4 days. It was the disease behind the Black Death of the 14th century, … Pneumonic plague, or lung-based plague, is the most virulent form of plague. From 1–7 days; may be a few days longer in immunised people who develop illness. It is caused by the bacterium, Yersinia pestis. NOTE: Unlike cats, dogs do not appear to develop pneumonic plague. Less frequently, the organism enters through a break in the skin by direct contact with tissue or body fluids of a plague–infected animal, for instance, in the process of skinning a rabbit or other animal. Plague or black death is an infection of rodents caused by Yersinia pestis and accidentially transmitted to humans by the bite of infected fleas. Plague is a highly contagious, life-threatening infection now present in the US mainly in rural or semirural areas of the Southwest. Spread of infection Incubation period. Any person with pneumonic plague may transmit the disease via droplets to other humans. Plague, infectious disease caused by Yersinia pestis, a bacterium transmitted from rodents to humans by the bite of infected fleas. Modes of Transmission. Strategy 1 Basic Information. Dog-to-human transmission was reported in a 2014 outbreak in Colorado. Mode of transmission. The bubonic plague is the most common form of infection and targets the victim’s lymphatic system. [] Survival of the bacillus in nature depends on flea-rodent interaction, and human infection does not contribute to the bacteria's persistence in nature. Plague bacteria are killed within a few hours of exposure to sunlight, although they may persist for several weeks in water and on moist grains and pulses. Plague is most commonly transmitted from rodent to human by the bite of an infected flea, especially the oriental rat flea Xenopsylla cheopis. Plague is a zoonotic disease that primarily affects rodents; humans are incidental hosts. After being taken up by macrophages, the bacteria proliferate in the affected lymph nodes, causing inflammation and swelling to occur, i.e., buboes. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague. Pneumonic plague occurs when Y. pestis infects the lungs, and is the most deadly form of the disease. Plague has caused some of the most-devastating epidemics in history. The infection exists in three major plague forms: bubonic, septic, and pneumonic. The disease follows urban and sylvatic cycles and is manifested in bubonic and pneumonic forms [note: bubo is derived from a Greek word for groin]. Plague is infamous for killing millions of people in Europe during the Middle Ages. Plague Disease. Bubonic plague can advance and spread to the lungs, which is the more severe type of plague called pneumonic plague. Incubation can be as short as 24 hours. Author: The Overmind Difficulty: Mega Brutal Gameplay. 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